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  • Berezina, G.; Svyatova, G.; Aimbetova, A. (National Laboratory Astana, Nazarbayev University, 2017-09-15)
  • Gritsenko, Dilyara; Pozharsky, Aleksandr; Deryabina, Nina; Kassenova, Aliya; Galiakparov, Nurbol (Genetika-Belgrade, 2019)
    The influenza is one of the most dangerous and widespread infectious diseases on the planet. A natural reservoir of the influenza A virus is wild waterfowl, which subsequently contribute to the spread of viral infection ...
  • Kalkamanova, I.; Tokanova, A.; Akilzhanova, A. (National Laboratory Astana, Nazarbayev University, 2017-09-15)
  • Kairov, U.; Molkenov, A.; Zhabagin, M.; Askapuli, A.; Abilmazhinova, A.; Akhmetova, A.; Yerezhepov, D.; Abilova, Zh.; Rahimova, S.; Zhumadilov, Zh.; Akilzhanova, A. (Nazarbayev University, 2013)
    The aim of the project is to define genetic architecture of Kazakh population by sequencing and analyzing whole exomes and whole genomes of Kazakhs living in different regions of Kazakhstan
  • Redrejo-Rodriguez, M.; Mursalimov, A.; Koshenov, Z.; Zhakupova, K.; Saparbaev, M. K.; Ishchenko, A. A.; Matkarimov, B. (Nazarbayev University, 2014)
    Human apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair enzyme involved in both base excision repair (BER) and nucleotide incision repair (NIR) pathways. In the BER pathway, APE1 cleaves DNA at AP sites and ...
  • Erper, Ismail; Ozer, Goksel; Kalendar, Ruslan; Avci, Sirin; Yildirim, Elif; Alkan, Mehtap; Turkkan, Muharrem (Journal of Fungi, 2021-03-21)
    A total of 132 Rhizoctonia isolates were recovered from red cabbage plants with root rot and wirestem symptoms in the province of Samsun (Turkey) between 2018 and 2019. Based on the sequence analysis of the internal ...
  • Erper, Ismail; Ozer, Goksel; Kalendar, Ruslan; Avci, Sirin; Yildirim, Elif; Alkan, Mehtap; Turkkan, Muharrem (Journal of Fungi, 2021-03-21)
    A total of 132 Rhizoctonia isolates were recovered from red cabbage plants with root rot and wirestem symptoms in the province of Samsun (Turkey) between 2018 and 2019. Based on the sequence analysis of the internal ...
  • Shevtsov, Alexandr; Ramanculov, Erlan; Shevtsova, Elena; Kairzhanova, Alma; Tarlykov, Pavel; Filipenko, Maxim; Dymova, Maya; Abisheva, Gulzada; Jailbekova, Aygul; Kamalova, Dinara; Chsherbakov, Andrei; Tulegenov, Samat; Akhmetova, Assel; Sytnik, Igor; Karibaev, Talgat; Mukanov, Kasim (Infection, Genetics and Evolution, 2015-08-01)
    Abstract Brucellosis is an endemic disease in Central Asia characterized by high infection rates in humans and animals. Currently, little is known about the genetic diversity of Brucella spp. circulating in the region, ...
  • Shevtsova, Elena; Vergnaud, Gilles; Shevtsov, Alexandr; Shustov, Alexandr; Berdimuratova, Kalysh; Mukanov, Kasim; Syzdykov, Marat; Kuznetsov, Andrey; Lukhnova, Larissa; Izbanova, Uinkul; Filipenko, Maxim; Ramankulov, Yerlan (FRONTIERS MEDIA SA, 2019-08-13)
    We describe the genetic diversity of 1327 Brucella strains from human patients in Kazakhstan using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA). All strains were assigned to the Brucella melitensis ...
  • Shevtsov, Vladislav; Kairzhanova, Alma; Shevtsov, Alexandr; Shustov, Alexandr; Kalendar, Ruslan; Abdrakhmanov, Sarsenbay; Lukhnova, Larissa; Izbanova, Uinkul; Ramankulov, Yerlan; Vergnaud, Gilles (Public Library of Science, 2021-05-17)
    Tularemia is a highly dangerous zoonotic infection due to the bacteria Francisella tularensis. Low genetic diversity promoted the use of polymorphic tandem repeats (MLVA) as first-line assay for genetic description. Whole ...
  • Razbekova, Madina; Issanov, Alpamys; Chan, Mei-Yen; Chan, Robbie; Yerezhepov, Dauren; Kozhamkulov, Ulan; Akilzhanova, Ainur; Chan, Chee-Kai (BMJ Publishing Group, 2021-02-05)
    Objectives There is limited published literature on the genetic risks of chronic inflammatory related disease (eg, obesity and cardiovascular disease) among the Central Asia population. The aim is to determine potential ...
  • Masoud, A.; Kravtsova, O. A.; Biktagirova, E. (Nazarbayev University, 2014)
    Currently, hypertension is recognized as one of the most common cardio-vascular diseases. Recent studies indicate the multifactorial nature of this disease, in which much emphasis is given to genetic factors for their ...
  • Jeong, Choongwon; Balanovsky, Oleg; Lukianova, Elena; Kahbatkyzy, Nurzhibek; Flegontov, Pavel; Zaporozhchenko, Valery; Immell, Alexander; Wang, Chuan-Chao; Ixan, Olzhas; Khussainova, Elmira; Bekmanov, Bakhytzhan; Zaibert, Victor; Lavryashina, Maria; Pocheshkhova, Elvira; Yusupov, Yuldash; Agdzhoyan, Anastasiya; Koshel, Sergey; Bukin, Andrei; Nymadawa, Pagbajabyn; Turdikulova, Shahlo; Dalimova, Dilbar; Churnosov, Mikhail; Skhalyakho, Roza; Daragan, Denis; Bogunov, Yuri; Bogunova, Anna; Shtrunov, Alexandr; Dubova, Nadezhda; Zhabagin, Maxat; Yepiskoposyan, Levon; Churakov, Vladimir; Pislegin, Nikolay; Damba, Larissa; Saroyants, Ludmila; Dibirova, Khadizhat; Atramentova, Lubov; Utevska, Olga; Idrisov, Eldar; Kamenshchikova, Evgeniya; Evseeva, Irina; Metspalu, Mait; Outram, Alan K.; Robbeets, Martine; Djansugurova, Leyla; Balanovska, Elena; Schiffels, Stephan; Haak, Wolfgang; Reich, David; Krause, Johannes (Nature Ecology & Evolution, 2019-04)
    The indigenous populations of inner Eurasia-a huge geographic region covering the central Eurasian steppe and the northern Eurasian taiga and tundra-harbour tremendous diversity in their genes, cultures and languages. In ...
  • Sydykova, K.; Sadykov, M.; Zhailauova, A.; Adilbayeva, A.; Myngbay, A.; Adarichev, V. A. (Nazarbayev University, 2014)
    Inbred murine strains are generated to insure genetic homogeneity and uniqueness and define immune characteristics, like major histocompatibility complex (MHC) haplotype, of the experimental model. Maintaining of the ...
  • Poddighe, Dimitri; Turganbekova, A.; Baymukasheva, Dana; Saduakas, Zhazira; Zhanzakova, Zhuldyz; Abdrakhmanova, S. (PLoS One, 2020-01-02)
    Background Celiac disease (CD) is a systemic immune-mediated disorder developing in HLA genetically predisposed individuals carrying HLA-DQ2 and/or HLA-DQ8 molecules. Recent evidences supported a predominant importance ...
  • Zholdybayeva, Elena V.; Talzhanov, Yerkebulan A.; Aitkulova, Akbota M.; Tarlykov, Pavel V.; Kulmambetova, Gulmira N.; Iskakova, Aisha N.; Dzholdasbekova, Aliya U.; Visternichan, Olga A.; Taizhanova, Dana Zh.; Ramanculov, Yerlan M. (Human Genomics, 2016)
    Background: After coronary stenting, the risk of developing restenosis is from 20 to 35 %. The aim of the present study is to investigate the association of genetic variation in candidate genes in patients diagnosed with ...
  • Zhumadilov, Zh.; Issayeva, R.; Berikkhanova, K.; Terlikbayeva, A.; Darisheva, M.; Amirov, B.; Rakhimova, S.; Akilzhanova, A. (Nazarbayev University, 2013)
    We designed a case-control study to examine demographic, clinical, social and cultural factors associated with tuberculosis in four regions of Kazakhstan. Cases included persons identified by the national tuberculosis ...
  • Chertov, Nikita; Vasilyeva, Yulia; Zhulanov, Andrei; Nechaeva, Yulia; Boronnikova, Svetlana (Forests, 2021-10-14)
    The Ural Mountains and the West Eurasian Taiga forests are one of the most important centers of genetic diversity for Larix sibirica Ledeb. Forest fragmentation negatively impacts forest ecosystems, especially due to the ...
  • Vasilyeva, Yulia; Chertov, Nikita; Nechaeva, Yulia; Sboeva, Yana; Pystogova, Nina; Boronnikova, Svetlana; Kalendar, Ruslan (Forests, 2021-07-28)
    In order to carry out activities aimed at conservation and rational use of forest resources; it is necessary to study the main forest-forming plant species in detail. Scots pine (Pinus sylvestris L., Pinaceae) is mainly ...
  • Akilzhanova, Ainur; Rakhimova, Saule; Kozhamkulov, Ulan; Kairov, Ulykbek; Kushugulova, Almagul R.; Terwilliger, Joseph; Lee, Joseph (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Objective: Metabolic syndrome (MS) is a cluster of inter-related and heritable metabolic traits, which collectively impart unsurpassed risk for atherosclerotic cardiovascular disease and type 2diabetes. Considerable work ...

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