Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency

dc.contributor.author	Adarichev, V. A.
dc.contributor.author	Sarkar, S.
dc.contributor.author	Kalamov, N.
dc.contributor.author	Brucker, J.
dc.contributor.author	Forde, T. S.
dc.contributor.author	Shekhani, M.T.
dc.contributor.author	Lyons, B.
dc.date.accessioned	2015-10-28T09:55:50Z
dc.date.available	2015-10-28T09:55:50Z
dc.date.issued	2013
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/560
dc.description.abstract	We found that Pgis2-congenic mice that carry genetically-deficient copy of C5(Hc) complement component were susceptible to collagen antibody-induced arthritis while inflammation was transient. Using differential gene expression analysis tools, we identified 20 genes whose down/up regulation in Pgis2-congenic mice might rescue C5 complement deficiency or, in a wider sense, rescue the function of the entire Pgis2 locus.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	first research week	ru_RU
dc.subject	arthritis	ru_RU
dc.subject	science	ru_RU
dc.title	Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency	ru_RU
dc.type	Abstract	ru_RU