Development of an optical biosensor for diagnosis of tuberculosis

Kanayeva, D.; Bekmurzayeva, A.; Bekniyazov, I.; Rakhmetova, A.; Sypabekova, M.; Ashikbayeva, Z.; Akan, M.; Wang, R.; Lum, J.; Li, Y.

NUR Home
→
13.Materials of Forums, Conferences and Projects
→
NU Research Week: abstracts
→
NU Research Week - I
→
View Item

dc.contributor.author	Kanayeva, D.
dc.contributor.author	Bekmurzayeva, A.
dc.contributor.author	Bekniyazov, I.
dc.contributor.author	Rakhmetova, A.
dc.contributor.author	Sypabekova, M.
dc.contributor.author	Ashikbayeva, Z.
dc.contributor.author	Akan, M.
dc.contributor.author	Wang, R.
dc.contributor.author	Lum, J.
dc.contributor.author	Li, Y.
dc.date.accessioned	2015-10-28T08:57:50Z
dc.date.available	2015-10-28T08:57:50Z
dc.date.issued	2013
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/554
dc.description.abstract	Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis. TB is the leading cause of morbidity and mortality in the developing world. Early and accurate diagnosis of TB would greatly enhance the treatment and prevention of the disease. Current methods of TB detection suffer from various limitations such as low specificity and sensitivity, being too complex and expensive. In the present work, we aim to develop an optical biosensor based on DNA aptamers, quantum dot (QD) crystals and magnetic nanoparticles (MNP) for detection of MPT64 protein, specific to M.tuberculosis. Aptamer-MNP conjugate is used for separation of MPT64 from solution, while aptamer-QD is used to detect its presence afterwards using fluorometer.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	first research week	ru_RU
dc.subject	healthcare problems	ru_RU
dc.subject	Tuberculosis control	ru_RU
dc.subject	optical biosensor	ru_RU
dc.title	Development of an optical biosensor for diagnosis of tuberculosis	ru_RU
dc.type	Abstract	ru_RU