Rage targeted strategies for Alzheimer`s Amyloid B peptide include blood brain barrier dysfunctions

dc.contributor.author	Askarova, Sholpan
dc.contributor.author	Tsoy, A.
dc.contributor.author	Lee, J.C-M.
dc.date.accessioned	2015-10-27T05:48:07Z
dc.date.available	2015-10-27T05:48:07Z
dc.date.issued	2013
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/504
dc.description.abstract	This study demonstrated that Aβ binding to RAGE at the CECs and astrocytes surface is required for NADPH oxidase complex assembling, resulting in subsequent ROS generation and phosphorylation of cPLA2α. Therefore, understanding precise molecular mechanisms underlying Aβ mediated oxidative damage may provide new insights into the development of preventive and treatment strategies for AD.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	Alzheimer’s disease	ru_RU
dc.subject	healthcare system	ru_RU
dc.title	Rage targeted strategies for Alzheimer`s Amyloid B peptide include blood brain barrier dysfunctions	ru_RU
dc.type	Abstract	ru_RU