Mapping of eco-social and genetic factors of susceptibility of tuberculosis among the population of the Rebuplic of Kazakhstan

Abstract

In this study combined design was used, which included: 1) Case-control study; 2) Molecular epidemiological study; and 3) Study of human genetic susceptibility to tuberculosis.This work is the first case-control study in Kazakhstan where complex factors of TB risk and their effects are estimated. The study confirmed the role of main risk factors of tuberculosis development in Kazakhstan: young age, single relationship status, living in rent apartment, smoking, diabetes and migration.