Epigenetic reprogramming of cancer cells under embryonic microenvironment

dc.contributor.author	Mu, X.
dc.contributor.author	Sultankulov, B.
dc.contributor.author	Agarwal, R.
dc.contributor.author	Mahjoub, A.
dc.contributor.author	Schott, T.
dc.contributor.author	Greco, N.
dc.contributor.author	Huard, J.
dc.contributor.author	Weiss, K.
dc.date.accessioned	2015-10-26T10:03:44Z
dc.date.available	2015-10-26T10:03:44Z
dc.date.issued	2014
dc.identifier.isbn	9786018046728
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/466
dc.description.abstract	The idea of epigenetic reprogramming of cancer cells by an embryonic microenvironment possesses potential interest from the prospect of both basic science and potential therapeutic strategies. Chick embryo extract (CEE) has been used for the successful expansion of many specific stem cells and has demonstrated the ability to facilitate DNA demethylation. The current study was conducted to compare the status of DNA methylation in highly metastatic and less metastatic osteosarcoma cells and to investigate whether CEE may affect the epigenetic regulation of tumor suppressor genes and thus change the metastatic phenotypes of highly metastatic osteosarcoma cells.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	epigenetic reprogramming	ru_RU
dc.subject	embryonic microenvironment	ru_RU
dc.subject	osteosarcoma cells	ru_RU
dc.subject	cell apoptosis	ru_RU
dc.subject	genes	ru_RU
dc.title	Epigenetic reprogramming of cancer cells under embryonic microenvironment	ru_RU
dc.type	Abstract	ru_RU