SNX 9 interacts with dynamin 2 and N-wasp to regulate focal adhesion disassembly and cell migration

dc.contributor.author	Zhubanchaliyev, A.
dc.contributor.author	Chao, W. T.
dc.contributor.author	Kunz, J.
dc.date.accessioned	2015-10-26T08:01:25Z
dc.date.available	2015-10-26T08:01:25Z
dc.date.issued	2014
dc.identifier.isbn	9786018046728
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/455
dc.description.abstract	The turnover of focal adhesions is essential for normal cell migration and tumor invasion, but the underlying mechanisms are poorly understood. We have previously shown that the disassembly of focal adhesions occurs by endocytosis of activated integrins from adhesion sites (1). We have further identified new components that mediate integrin endocytosis. Here, we provide the initial characterization of one of these components, sorting nexin 9 (Snx9), an endocytic adaptor protein not previously implicated in cell adhesion and migration.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	cell migration	ru_RU
dc.subject	Snx9 regulation	ru_RU
dc.subject	cell biological	ru_RU
dc.subject	biochemical	ru_RU
dc.title	SNX 9 interacts with dynamin 2 and N-wasp to regulate focal adhesion disassembly and cell migration	ru_RU
dc.type	Abstract	ru_RU