Browsing by Subject "immunoglobulin E"

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Cutting edge: IgE plays an active role in tumor immunosurveillance in mice

Nigro, Elisa A.; Brini, Anna T.; Yenagi, Vijay A.; Ferreira, Lorena M.; Achatz-Straussberger, Gertrude; Ambrosi, Alessandro; Sanvito, Francesca; Soprana, Elisa; Van Anken, Eelco; Achatz, Gernot; Siccardi, Antonio G.; Vangelista, Luca (Journal of Immunology, 2016-10-01)

Exogenous IgE acts as an adjuvant in tumor vaccination in mice, and therefore a direct role of endogenous IgE in tumor immunosurveillance was investigated. By using genetically engineered mice, we found that IgE ablation ...
Split core technology allows efficient production of virus-like particles presenting a receptor-contacting epitope of human IgE

Baltabekova, A. Zh.; Shagyrova, Zh. S.; Voykov, M.; Ramanculov, E. M.; Shustov, A. V. (Nazarbayev University, 2014)

Immunoglobulin E (IgE) plays a central role in type I hypersensitivity including allergy and asthma. Novel treatment strategy envisages development of a therapeutic vaccine designed to elicit autologous blocking antibodies ...