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Browsing by Subject "cancer stem cells"

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Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure

Francipane, M. G.; Bulanin, Denis; Lagasse, E. (MDPI, 2019-04-12)

5-Fluorouracil (5-FU) remains the gold standard of first-line treatment for colorectal cancer (CRC). Although it may initially debulk the tumor mass, relapses frequently occur, indicating the existence of cancer cells that ...
Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells

Francipane, M. G.; Bulanin, D.; Lagasse, E. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)

Current first-line chemotherapy generally consists of cytotoxic agents. While these agents may initially control disease by effectively debulking tumors, the tumors invariably recur due to the ability of cancer stem cells ...
Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells

Francipane, M.; Bulanin, D.; Lagasse, E. (National Laboratory Astana, Nazarbayev University, 2017-09-15)
Паракринные регуляторы раковых стволовых клеток толстой кишки / Paracrine regulators of colon cancer stem cells

Ogay (Огай), Vyacheslav (Вячеслав); Issabekova (Исабекова), A.S. (А.С.) (Вестник КазНУ. Серия биологическая, 2014)

Раковые стволовые клетки основная причина возобновления болезни после лечения. Для эффективной борьбы с этими клетками необходимо понимание механизмов выживание этих клеток и их стимуляторов. В данной работе оценено влияние ...
Саморегуляция раковых стволовых клеток толстой кишки / Colon cancer stem cells self regulation

Ogay (Огай), Vyacheslav (Вячеслав) (Вестник КазНУ. Серия биологическая. №1/1 (60). 2014, 2014)

Colon cancer high death rate and low percentage of recovery depend on tumor initiating cancer stem cells (CSCs). CSCs have ability such as survival in stress condition, absence of sensitivity to apoptose. These properties ...